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Tell your doctor and pharmacist if you are allergic to premarin, aspirin, tartrazine a yellow dye in some processed foods and drugs , or any other drugs.

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There have not been sufficient numbers of geriatric women involved in clinical studies utilizing PREMARIN Vaginal Cream to determine whether those over 65 years of age differ from younger subjects in their response to PREMARIN Vaginal Cream.
Patients with a history of VTE or known thrombophilic states have an increased risk of VTEHRT may add to this riskHRT is therefore contraindicated in these patientssee section 4.3Personal or strong family history of thromboembolism or recurrent spontaneous abortion should be investigated in order to exclude a thrombophilic predisposition.
In the absence of comparable datathese risks should be assumed to be similar for other doses of CE and MPAand other combinations and dosage forms of estrogens and progestins.
In the absence of comparable datathese risks should be assumed to be similar for other doses of CE and other dosage forms of estrogens
Hormone replacement therapyHRTis associated with a 1.3-3 fold risk of developing venous thromboembolismVTEi.edeep vein thrombosis or pulmonary embolismThe occurrence of such an event is more likely in the first year of HRT than latersee section 4.8
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she also takes coumadin and diabeta and premarin.