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Bupropion is the same active ingredient that is in zyban.

Information about Zyban.

They function in different waysare manufactured by different companies and vary slightly in the way they are taken.

Zyban is contraindicated in patients with a history of bipolar disorder as it may precipitate a manic episode during the depressed phase of their illness.

Do not crush or chew this medicationDoing so can release all of the drug at onceincreasing the risk of side effectsincluding seizuresAlsodo not split the tablets unless they have a score line and your doctor or pharmacist tells you to do soSwallow the whole or split tablet without crushing or chewing.

It is not known whether bupropion will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant while using this medicine.

But varenicline also limits the effect of inhaled nicotine on these receptors tooSo if someone taking the medicine does smokethe nicotine inhaled will have little to no effect on receptors in the brainrendering the act of smoking chemically impotentThis consequently makes the act of smoking less desirable.

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zyban has the advantage that, unlike nrt, it contains no nicotine, which is a harmful substance even when taken for the ultimately healthful purpose of quitting smoking.