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Cdiffficile produces toxins A and B which contribute to the development of CDADHypertoxin producing strains of Cdifficile cause increased morbidity and mortalityas these infections can be refractory to antimicrobial therapy and may require colectomyCDAD must be considered in all patients who present with diarrhea following antibacterial useCareful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
Lincomycin is a lincosamide antibiotic that comes from the yeast Streptomyces lincolnensisLincomycin has been shown to be active in vitro against the following microorganismsAerobic gram-positive cocciStreptococcus pyogenes and Viridans group streptococciAerobic gram-positive bacilliCorynebacterium diphtheriaeAnaerobic gram-positive non-sporeforming bacilliPropionibacterium acnesAnaerobic gram-positive sporeforming bacilliClostridium tetani and Clostridium perfringens
To reduce the development of drug-resistant bacteria and maintain the effectiveness of LINCOCIN and other antibacterial drugsLINCOCIN should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteriaWhen culture and susceptibility information are availablethey should be considered in selecting or modifying antibacterial therapyIn the absence of such datalocal epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Lincomycin has been shown to be active in vitro against the following microorganismshoweverthe safety and efficacy of Lincocin in treating clinical infections due to these organisms have not been established in adequate and well controlled trials.
It is given as a shot into a muscle or as an infusion into a vein over a period of time.
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lincocine lincomycin works by killing or stopping the growth of bacteria causing your infection.