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Food was shown to reduce both the rate and extent of absorption of capecitabinesee CLINICAL PHARMACOLOGYIn all clinical trialspatients were instructed to administer XELODA within 30 minutes after a mealIt is recommended that XELODA be administered with foodsee DOSAGE AND ADMINISTRATION
Capecitabine is a type of chemotherapy called an anti metaboliteThe body changes capecitabine into a common chemotherapy drug called fluorouracilIt stops cells making and repairing DNACancer cells need to make and repair DNA so they can grow and multiply.
Table 17 Efficacy of XELODA and Docetaxel Combination vs Docetaxel Monotherapy.
Patients receiving concomitant capecitabine and oral coumarin-derivative anticoagulant therapy should have their anticoagulant responseINR or prothrombin timemonitored closely with great frequency and the anticoagulant dose should be adjusted accordinglysee BOX WARNING and DRUG INTERACTIONS
Call your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800FDA-1088.
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