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Many drugs can interact with glyburide and metforminmaking this medicine less effective or increasing your risk of lactic acidosisThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed hereTell your doctor about all your current medicines and any medicine you start or stop using.
-As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise AloneStarting dose1.25 mg-250 mg orally once a dayConsider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucoseFBGgreater than 200 mg/dL or HbA1c greater than 9Maintenance DoseIncrease in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose10 mg-2000 mg per day.
In type 1 and type diabetesthere are symptoms particularly unique to womenMore than half of women with polycystic ovary syndromeor PCOSdevelop type 2 diabetes by the age of 40Women have a higher risk for heart diseaseheart attackand strokeWomen also have lower survival rates and a poorer quality of life after a heart attack than menWomen have a higher risk for blindness and depressionIn women with diabetesthegoodor HDL cholesterol dropswhich puts them at greater risk of heart diseaseVaginal itching and pain due to vaginal and oral yeast infectionsVaginal paindrynessreduced libidosex driveor decreased vaginal sensation during sex due to blood flow problems to the genitalsIncreased urinary tract infectionsor UTIsThere are signs and symptoms of both types of diabetes that are common in men and womenSores or wounds that do not heal Numbness and/or tingling in the hands or feet Fatigue Increased hunger Increase thirst Increased urination Blurred vision Unexplained weight loss If you are planning to become pregnanttalk with your doctor about managing your diabetes during pregnancy to avoid complicationsGestational diabetes occurs during pregnancy and causes blood sugar levels too become to highGestational diabetes can be managed with dietand if necessary medicationIt usually goes away once the baby is bornHoweverif you have gestational diabetes during pregnancy it increases your risk of developing type 2 diabetes later.
This is not a complete list of side effects and others may occurCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.
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