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The liquid form of Diflucan contains sucroseTalk to your doctor before using this form of fluconazole if you have a problem digesting sugars or milk.
The same mg/kg dose as for infantstoddlers and children should be given every 72 hours.
Coadministration of terfenadine is contraindicated in patients receiving Diflucan at multiple doses of 400 mg per day or higher based upon results of a multiple dose interaction studyCoadministration of other medicinal products known to prolong the QT interval and which are metabolised via the cytochrome P450CYP3A4 such as cisaprideastemizolepimozidequinidine and erythromycin are contraindicated in patients receiving fluconazolesee sections 4.4 and 4.5
Recurrent150 mg PO qDay for 10-14 days followed by 150 mg once weekly for 6 months.
VoriconazoleCYP2C9CYP2C19 and CYP3A4 inhibitorCoadministration of oral voriconazole400 mg Q12h for 1 daythen 200 mg Q12h for 2.5 daysand oral fluconazole400 mg on day 1then 200 mg Q24h for 4 daysto 8 healthy male subjects resulted in an increase in C max and AUC of voriconazole by an average of 5790CI20107and 7990CI40128respectivelyThe reduced dose and/or frequency of voriconazole and fluconazole that would eliminate this effect have not been establishedMonitoring for voriconazole associated adverse events is recommended if voriconazole is used sequentially after fluconazole.
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