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In 2004, when merck s brand of simvastatin, known as zocor, was about to go off patent, merck teamed up with schering-plough to produce a new patented product called vytorin, a combination of simvastatin and zetia.

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All of the clinical studies that have been performed are limited to primary hypercholesterolemiaPrimary hypercholesterolemia is due to a genetic defect in cholesterol metabolismwhereas secondary hypercholesterolemia is due to secondary factors such as obesitydiabetes mellitusphysical inactivityandor nutritionUnfortunatelythere are no data to support the use of ezetimibe in patients with secondary hypercholesterolemiaThereforethe findings of these trialssome of which are summarized hereapply only to those patients with primary hypercholesterolemia.

This drug may increase the risk of liver damagewhen taken with astatinor muscle damage when taken with a fibrate orstatinTell your doctor right away if you experience any of the following symptomssigns of liver problemssuch as severe stomach/abdominal painpersistent nausea/vomitingyellowing eyes/skindark urinemuscle pain/tenderness/weaknessespecially with fever or unusual tiredness

The following information is NOT intended to endorse drugs or recommend therapyWhile these reviews might be helpfulthey are not a substitute for the expertiseskillknowledge and judgement of healthcare practitioners in patient care.

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