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On a body-weight basis, these doses are 600 times in mice and 100 times in rats the maximum recommended human dose mrhd for the hydrochlorothiazide component of triamterene and hydrochlorothiazide tablets, 50 mg day or 1 mg kg day based on a 50 kg patient .
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Triamterene counteracts potassium loss caused by hydrochlorothiazide.
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Generic name s triamterene-hydrochlorothiazid.
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Duration of diuretic activity and effective dosage range of the hydrochlorothiazide and triamterene components are similar.
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in the combined administration of enalapril and potassium-sparing diuretics such as spironolactone , triamterene, amiloride or potassium supplements may lead to greatly increased potassium blood levels.