A decrease in fibula growth rate was observed in premature infants given oral tetracycline in doses of 25 mg kg every six hours.

Dermatologists sometimes prescribe a tetracycline-type of antibiotic for low-grade acne as a long-term therapy.

Tetracycline must be taken on an empty stomach to be fully effective.

This protein actively exports tetracycline out of the cell rendering cells harboring this gene more resistant to the drug.