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I have been taking synthroid 175 for quite a while, but have been on diltiazem 180 for 2 yrs now and have lost almost 75 of my hair in the back of my scalp.
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Levothyroxine has a narrow therapeutic indexRegardless of the indication for usecareful dosage titration is necessary to avoid the consequences of overor under-treatmentThese consequences includeamong otherseffects on growth and developmentcardiovascular functionbone metabolismreproductive functioncognitive functionemotional stategastrointestinal functionand on glucose and lipid metabolismMany drugs interact with levothyroxine sodium necessitating adjustments in dosing to maintain therapeutic responsesee DRUG INTERACTIONS
The patient should be monitored closely to avoid undertreatment or overtreatmentUndertreatment may have deleterious effects on intellectual development and linear growthOvertreatment has been associated with craniosynostosis in infantsand may adversely affect the tempo of brain maturation and accelerate the bone age with resultant premature closure of the epiphyses and compromised adult stature.
The list of drug-thyroidal axis interactions in Table 2 may not be comprehensive due to the introduction of new drugs that interact with the thyroidal axis or the discovery of previously unknown interactionsThe prescriber should be aware of this fact and should consult appropriate reference sourcese.gpackage inserts of newly approved drugsmedical literaturefor additional information if a drug-drug interaction with levothyroxine is suspected.
Fatigueincreased appetiteweight lossheat intolerancefeverexcessive sweating;
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if someone feels that their weight gain and synthroid use are connected, it is necessary to discuss it with the doctor and perhaps explore other methods of treatment, such as natural tsh replacement, or even a supplement of t3.