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FlecainideA study of healthy volunteers showed that the concomitant administration of flecainide and verapamil may have additive effects on myocardial contractilityAV conductionand repolarizationConcomitant therapy with flecainide and verapamil may result in additive negative inotropic effect and prolongation of atrioventricular conduction.
Verapamil is excreted in human milkBecause of the potential for adverse reactions in nursing infants from verapamilnursing should be discontinued while verapamil is administered.
Older adults may be more sensitive to the side effects of this drugespecially constipationor swelling ankles/feet.
Verapamil is also used to prevent chest painanginaIt may help to increase your ability to exercise and decrease how often you may get angina attacksVerapamil is also used to control your heart rate if you have a fast/irregular heartbeatsuch as atrial fibrillationIt helps to lower the heart ratehelping you to feel more comfortable and increase your ability to exercise.
In overdosetablets of Isoptin SR have occasionally been reported to form concretions within the stomach or intestinesThese concretions have not been visible on plain radiographs of the abdomenand no medical means of gastrointestinal emptying is of proven efficacy in removing themEndoscopy might reasonably be considered in cases of massive overdose when symptoms are unusually prolonged.
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