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Anyone handling hydrea should wash their hands before and.
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HYDREA is contraindicated in patients who have demonstrated a previous hypersensitivity to hydroxyurea or any other component of the formulation.
To decrease the risk of contactadvise caregivers to wear disposable gloves when handling HYDREA or bottles containing HYDREAWash hands with soap and water before and after contact with the bottle or capsules when handling HYDREADo not open HYDREA capsulesAvoid exposure to crushed or opened capsulesIf contact with crushed or opened capsules occurs on the skinwash affected area immediately and thoroughly with soap and waterIf contact with crushed or opened capsules occurs on the eye(sthe affected area should be flushed thoroughly with water or isotonic eyewash designated for that purpose for at least 15 minutesIf the powder from the capsule is spilledimmediately wipe it up with a damp disposable towel and discard in a closed containersuch as a plastic bagas should the empty capsulesThe spill areas should then be cleaned three times using a detergent solution followed by clean waterKeep the medication away from children and petsContact your doctor for instructions on how to dispose of outdated capsules.
A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.
Secondary MalignanciesThere is a very low risk of developing leukemia or skin cancer due to treatment with this medicationwhich can occur many years after treatmentThis is most often associated with long-term treatmentRadiation RecallRadiation recall is when the administration of a medication causes a skin reaction that looks like a sunburnrednessswellingsorenesspeeling skinin areas where radiation was previously givenNotify your oncology team if you notice this side effectTreatment can include topical steroid ointments and a delay in your next chemotherapy doseTumor Lysis SyndromeIf there are a large amount of tumor cells in your body prior to treatmentyou are at risk for tumor lysis syndromeThis happens when the tumor cells die too quickly and their waste overwhelms the bodyYou may be given a medicationallopurinoland IV fluids to help prevent thisIf you experience nauseavomitingdiarrhea or become lethargicdrowsysluggishnotify your oncology team right awayTLS can affect your kidney functionYour provider will monitor your kidney function with blood workNotify your provider if you have little or no urine outputMucositisCertain cancer treatments can cause sores or soreness in your mouth and/or throatNotify your oncology care team if your mouthtongueinside of your cheek or throat becomes whiteulcerated or painfulPerforming regular mouth care can help prevent or manage mouth soresIf mouth sores become painfulyour doctor or nurse can recommend a pain relieverLiver ToxicityThis medication can cause liver toxicitywhich your oncology care team may monitor for using blood tests called liver function testsNotify your healthcare provider if you notice yellowing of the skin or eyesyour urine appears dark or brownor you have pain in your abdomenas these can be signs of liver toxicity.
For pregnant womenHydroxyurea can harm a fetusThis is based on findings from animal studiesand on our knowledge of how the drug works.
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