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Htm precose acarbose is a prescription drug used to treat type 2 diabetes.
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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Patients Receiving Sulfonylureas or InsulinSulfonylurea agents or insulin may cause hypoglycemiaPrecose given in combination with a sulfonylurea or insulin may cause a further lowering of blood glucose and may increase the potential for hypoglycemiaIf hypoglycemia occursappropriate adjustments in the dosage of these agents should be madeVery rarelyindividual cases of hypoglycemic shock have been reported in patients receiving Precose therapy in combination with sulfonylureas and/or insulin.
In contrast to sulfonylureasPrecose does not enhance insulin secretionThe antihyperglycemic action of acarbose results from a competitivereversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymesPancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestinewhile the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharidestrisaccharidesand disaccharides to glucose and other monosaccharides in the brush border of the small intestineIn diabetic patientsthis enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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