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14 it was the first nonaluminium, noncalcium-based binder available in the united states and europe and was initially produced and marketed as the hydrochloride renagel , genzyme corporation, cambridge, ma, usa .

Information about Renagel.
In interaction studies in healthy volunteersRenagel had no effect on the bioavailability of digoxinwarfarinenalapril or metoprolol.
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For patients previously on phosphate bindersRenagel should be given on a gram for gram basis with monitoring of serum phosphorus levels to ensure optimal daily doses.
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