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Safety and effectiveness in pediatric patients have not been established in adequate and wellcontrolled trialssee WARNINGSWithdrawal
Fast or pounding heartbeatstremorsa very slow heart ratefewer than 60 beats per minutefeeling short of breatheven with mild exertionswellingrapid weight gainconfusionhallucinationsflu symptomsurination problemsor feeling like you might pass out.
Tricyclic antidepressantsfor exampleamitriptylineElavilEndepimipramineTofranildesipramineNorpraminand clomipramineAnafranilcan block the blood pressure lowering effects of CatapresThis may cause blood pressure to rise.
Hypertension may develop early and may be followed by hypotensionbradycardiarespiratory depressionhypothermiadrowsinessdecreased or absent reflexesweaknessirritability and miosisThe frequency of CNS depression may be higher in children than adultsLarge overdoses may result in reversible cardiac conduction defects or dysrhythmiasapneacoma and seizuresSigns and symptoms of overdose generally occur within 30 minutes to two hours after exposureAs little as 0.1 mg of clonidine has produced signs of toxicity in children.
Your doctor may prescribe a low-salt or low-sodium dietFollow these directions carefully.
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the patient had abruptly discontinued his clonidine five days prior to admission.