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Tell your doctor or pharmacist that you are taking Cardizem CD capsules or Cardizem tablets if you are about to be started on any new medicine.

In a healthy volunteer cross-over studyN=10co-administration of a single 20 mg dose of simvastatin at the end of a 14 day regimen with 120 mg BID diltiazem SR resulted in a 5-fold increase in mean simvastatin AUC versus simvastatin aloneSubjects with increased average steady-state exposures of diltiazem showed a greater fold increase in simvastatin exposureComputer-based simulations showed that at a daily dose of 480 mg of diltiazeman 8-to 9-fold mean increase in simvastatin AUC can be expectedIf co-administration of simvastatin with diltiazem is requiredlimit the daily doses of simvastatin to 10 mg and diltiazem to 240 mg.

These medicines may cause dizziness and fainting in some patientsespecially when you first start to use themMake sure you know how you react to these medicines before you drive a caroperate machineryor do anything else that could be dangerous if this happens to you.

If you are being treated for high blood pressurekeep using this medication even if you feel wellHigh blood pressure often has no symptomsYou may need to use blood pressure medication for the rest of your life.

CARDIZEM 90-mg scored tablets are supplied in bottles of 100NDC 0187-0791-47Each greenoblong tablet is engraved with CARDIZEM on one side and 90 mg on the other.

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