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Irrespective of the drug chosen to reverse naltrexone hydrochloride blockade, the patient should be monitored closely by appropriately trained personnel in a setting equipped and staffed for cardiopulmonary resuscitation.
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Patients taking REVIA may not benefit from opioid containing medicinessuch as cough and cold preparationsantidiarrheal preparationsand opioid analgesicsIn an emergency situation when opioid analgesia must be administered to a patient receiving REVIAthe amount of opioid required may be greater than usualand the resulting respiratory depression may be deeper and more prolongedsee PRECAUTIONS
This could result in potentially life-threatening opioid intoxicationrespiratory compromise or arrestcirculatory collapseetcif the patient uses previously tolerated doses of opioidsCases of opioid overdose with fatal outcomes have been reported in patients after discontinuing treatment.
Patients taking REVIA may not benefit from opioid containing medicinessuch as cough and cold preparationsantidiarrheal preparationsand opioid analgesicsIn an emergency situation when opioid analgesia must be administered to a patient receiving REVIAthe amount of opioid required may be greater than usualand the resulting respiratory depression may be deeper and more prolongedsee PRECAUTIONS
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