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Special SensesInfrequent were accommodation abnormality and dry eyeAlso observed were deafnessdiplopiaincreased intraocular pressureand mydriasis.
Very common10or moreInsomniaup to 45agitationup to 31.9abnormal dreamsup to 13
Mood or behavior changesanxietypanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallymore depressedor have thoughts about suicide or hurting yourself.
Bupropion is an NDRI antidepressant that has been available for over 15 years for major depressive disorder and over 6 years as an aid to smoking cessationData indicate that bupropion may be effective as a treatment for ADHD and in helping obese patients lose weightalthough the use of bupropion in these conditions is not approved by the FDAand additional studies are needed in both areasFor bipolar disorderencouraging evidence suggests that not only is bupropion effective for depressive episodesbut it also appears to have a smaller risk of inducing a manic switchthese studies are rather small and further investigation is requiredAmong all the newer antidepressants in the United Statesbupropion appears to have among the lowest incidence of sexual dysfunctionweight gainand somnolenceRecentlya once-daily formulationbupropion XLwas developed with the goal of further improving tolerability and complianceFuture studies should investigate the tolerability advantages of this formulationDue to its unique profilebupropion has played and will continue to play an important role in the treatment of major depressive disorder.
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