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If you your child miss a dose of nexium , and remember within 12 hours, take the tablet sachet as soon as possible.

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Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the HKATPase in the gastric parietal cellThe Sand R-isomers of omeprazole are protonated and converted in the acidic compartment of the parietal cell forming the active inhibitorthe achiral sulphenamideBy acting specifically on the proton pumpesomeprazole blocks the final step in acid productionthus reducing gastric acidityThis effect is dose-related up to a daily dose of 20 to 40 mg and leads to inhibition of gastric acid secretion.

Use of NEXIUM in pediatric patients 1 month to less than 1 year of age for treatmentup to 6 weeksof erosive esophagitis due to acid-mediated GERD is supported by extrapolation of results from adequate and well-controlled studies for adults and safetypharmacokineticand pharmacodynamic studies performed in pediatric patientssee DOSAGE AND ADMINISTRATIONADVERSE REACTIONSCLINICAL PHARMACOLOGYand Clinical Studies

NEXIUM For Delayed-Release Oral Suspension should be administered as follows:

Several published observational studies suggest that proton pump inhibitorPPItherapy may be associated with an increased risk for osteoporosis-related fractures of the hipwristor spineThe risk of fracture was increased in patients who received high-dosedefined as multiple daily dosesand long-term PPI therapya year or longerPatients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treatedPatients at risk for osteoporosis-related fractures should be managed according to established treatment guidelinessee DOSAGE AND ADMINISTRATION and ADVERSE REACTIONS

You may be more likely to have a broken bone while taking this medicine long term or more than once per day.

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