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Continue to use colchicine even if you feel well.

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Colchicine is contraindicated in patients with renal or hepatic impairment who are taking a P-gp inhibitore.gciclosporinverapamil or quinidineor a strong CYP3A4 inhibitore.gritonaviratazanavirindinavirclarithromycintelithromycinitraconazole or ketaconazolesee section 4.3

Musculoskeletalmyopathyelevated CPKmyotoniamuscle weaknessmuscle painrhabdomyolysis.

Gout is rare in pediatric patientsthe safety and effectiveness of colchicine capsules in pediatric patients has not been evaluated in controlled studies.

Colchicine comes as a tablet to take by mouth with or without foodWhen colchicine is used to prevent gout attacks or to treat FMFit is usually taken once or twice a dayWhen colchicine is used to relieve the pain of a gout attackone dose is usually taken at the first sign of pain and a secondsmaller dose is usually taken one hour laterIf you do not experience relief or have another attack within several days after treatmenttalk to your doctor before taking additional doses of medicationFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake colchicine exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.

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