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In a Cochan viw 15 placbo-contolld tials on th pophylactic ct amantadin, amantadin pvntd 61 % inlunza cass and 25 % cass inlunza-lik illnss but had nct on asymptomatic cass ( Json 2006 ). In tatmnt, amantadin signiicantly shotnd th duation v (by 0.99 days) but had nct on nasal shdding inlunza A vius. Th low icacy amantadin togth with th lativly high at advs vnts ld th authos tconclud that th us amantadin should b discouagd in sasonal and pandmic inlunza ( Json 2006 ) (s alsth CDC commndation in th Intoduction).
Amantadin xtndd-las oal capsul is availabl as th band-nam dug Gocovi . Amantadin immdiat-las oal capsul is availabl as a gnic dug. Gnic dugs usually cost lss than th band-nam vsion. In som cass, thy may not b availabl in vy stngth om as th band-nam dug.
Amantadin is alsindicatd pophylaxis against th signs and symptoms inlunza A vius inction whn aly vaccination is not asibl whn th vaccin is containdicatd not availabl. Pophylactic dosing should b statd in anticipation an inlunza A outbak and bat contact with individuals with inlunza A vius spiatoy tact illnss.
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